Stimulates synthesis of proteoglycans and glycosaminoglycans — the structural molecules that form cartilage matrix. HCl form is preferred over Sulfate.
Chondroitin
Inhibits cartilage-degrading enzymes and draws water into the cartilage matrix, maintaining its cushioning and shock-absorbing properties. Works synergistically with Glucosamine.
UC-II® Undenatured Type II Collagen
Works via oral tolerance. Activates regulatory T-cells that migrate to joints and release anti-inflammatory cytokines — stopping immune attack on cartilage.
OptiMSM®
Organic bioavailable sulfur that inhibits NF-κB and pro-inflammatory cytokines (IL-1, IL-6, TNF-α). Required building block for collagen synthesis. Reduces joint swelling and oxidative damage.
Green Lipped Mussel
Uniquely rich in ETA omega-3. Inhibits both COX-1 and LOX pathways simultaneously — blocking prostaglandins AND leukotrienes.
Boswellia
Boswellic acids (AKBA) are potent 5-LOX inhibitors. NSAID-like effect on joint pain and swelling without gastric side effects.
Hyaluronic Acid
Primary component of synovial fluid. Oral supplementation increases joint HA concentration and viscosity, reducing dry, grinding joints.
Curcumin
Inhibits NF-κB, COX-2, and iNOS — the three master inflammatory pathway regulators. Works synergistically with Boswellia and MSM.
Ginger
Proven analgesic compound. Directly translates to improved comfort and willingness to move, making results visible to pet parents early.
Vitamin C
Essential cofactor for collagen synthesis and a potent antioxidant protecting chondrocytes from oxidative damage.
Rosehip Powder
Standardized Rosa canina extract with GOPO — a natural anti-inflammatory compound with clinical evidence in arthritis.
How does the chew work?
STEP 1: REBUILDS THE FOUNDATION.
Joint problems don't start on the surface. Our chew delivers Glucosamine HCl, Chondroitin Sulphate, UC-II® Collagen, and OptiMSM® directly into your dog's system — the structural building blocks that cartilage, synovial fluid, and connective tissue need to repair and hold up over time.
STEP 2: WORKS DEEP INTO THE JOINT.
As these actives absorb, the Advanced 5 Stack — Boswellia, Hyaluronic Acid, Green-Lipped Mussel, Turmeric, and Ginger — goes to work inside the joint capsule. Inflammation pathways are blocked, synovial fluid is replenished for lubrication, and cartilage is actively protected from further breakdown.
STEP 3: HELPS STOP SYMPTOMS.
Once the joint environment is restored and inflammation is under control, the visible signs begin to reverse. This helps eliminate stiffness on rising, reluctance to climb stairs, limping after walks, and joint-related slowdown — getting your dog moving freely and confidently again.
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